Fox’s gripping medical drama Doc is officially making its return, and fans won’t have to wait much longer to scrub back in. We knew Doc season 2 would start airing this fall, but now we have an official premiere date. The network has just announced that the highly anticipated second season will premiere on Tuesday, Sept. 23, 2025. The date was revealed in the newly released teaser trailer that Fox dropped on July 21.
When Doc returns with its second season on Sept. 23, you can expect the first episode to start airing at 9:00 p.m. ET/8:00 p.m. CT on Fox. Going forward, a new episode will air every Tuesday night at the same exact time. Murder in a Small Town season 2 will air right before it at 8/7c. However, please note that a premiere date hasn't been announced yet for the second season of Murder in a Small Town.
Check out the short yet exciting teaser trailer for Doc season 2 below, which features a first look at new cast member Felicity Huffman as Dr. Joan Ridley!
Doc was created by Barbie Kligman (Magnum P.I., Secrets and Lies). It's based on the Italian series Doc — Nelle tue mani, which was inspired by the true story of Dr. Pierdante Piccioni, a medical physician who lost over a decade of his memory after a traumatic brain injury due to a car accident.
The medical drama tells a similar story, centering on Dr. Amy Larsen, a brilliant physician whose life is upended after a car accident wipes out eight years of her memory. Now, she's determined to rebuild her life and career from the ground up, facing the challenges of relearning who she was while adapting to the changes in her personal and professional world. Molly Parker stars in the leading role as Amy. Also in the cast are Omar Metwally, Jon Ecker, Amirah Vann, Anya Banerjee, Patrick Walker, and Charlotte Fountain-Jardim.
In January 2025, the medical drama premiered its first episode, which quickly drew in a massive audience. In fact, Doc had the most successful premiere of any new Fox series in the past five years. Talk about an impressive feat!
The medical drama continued to draw in an audience as the first season went on, making it a no-brainer for Fox to renew it for an additional installment. Doc season 2 is confirmed to consist of a whopping 22 episodes. This is a huge jump from season 1's episode count, which was 10 episodes. It looks like the network has strong faith in the show’s potential, and in my opinion, this expanded episode order is well-deserved.
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