Grey’s Anatomy fans, brace yourselves. Your emotional stability might be about to be tested. If you recall from the season 21 finale, a massive explosion happens at Grey Sloan Memorial, leaving the fates of several beloved characters hanging by a thread. Now, with season 22 just around the corner, a new interview has everyone on edge about whether Link (Chris Carmack), Head of Orthopedic Surgery, will survive the catastrophic event.
The explosion erupts on Grey Sloan’s OR floor, throwing doctors and staff into immediate chaos. Monica, Jules, and Bailey are shown on the floor having a conversation, while Link is inside an operating room, in the middle of a surgery. We never find out if these four characters make it out of the blast alive at the end of the twenty-first season, and this is what's been on fans' minds ever since.

Now, Camilla Luddington, who plays Jo, Link's wife, has added fuel to the fire in a recent interview. While speaking to Us Weekly about filming the twenty-second season, Luddington seemed to hint that her character will return. This shouldn't come as a surprise, given that the last time we saw Jo in Grey's Anatomy season 21, she was outside the hospital when the explosion happened.
However, Luddington avoided giving any clear answers about Link’s fate. But the comments she did make have only made us more worried that Link might not make it out alive. When discussing how she first learned about the explosion, she expressed how she hadn't anticipated that things would go so dramatically wrong for her character and Link. She admitted that she initially believed Jo and Link’s happiness might actually last, only to soon find out, as a veteran of the show, that Grey’s Anatomy was about to deliver another shocking twist.
“I should have known. It didn’t occur to me — and I’m a vet of 13 years of that show — and I was like, ‘Damn things are going so well,’ like, so naive. And I’m like, ‘Oh, of course. No, no, no, no, there’s gonna be an explosion, and my husband will be in it. I should have known!’”
She also mentioned that the Grey's Anatomy season 22 premiere wasn't her favorite to film since it was really "traumatic" for the cast and crew. While we don't know who exactly won't survive the explosion, Link seems to be in the most danger. Jo had just revealed to Link that they were expecting twins in the season 21 finale. If you know anything about Grey's Anatomy, this show loves to deliver good news only to immediately throw in a life-threatening disaster to shock fans.
There's a possibility that we'll see Link initially survive the explosion. Maybe we'll see him in a coma in the hospital in the season 22 premiere. But then his condition could suddenly take a turn for the worse, and Jo is left a widow and a single mother. It wouldn't be the first time the medical drama series has done something like this, where a character initially survives a life-threatening event only to face tragic consequences later. Obviously, we want to see Link make it out alive and him and Jo live happily together. But it's always best to prepare for the worst.
Grey's Anatomy season 22 is set to premiere on ABC on Thursday, Oct. 9, 2025.